Sofosbuvir is a part of a category of drugs you know as polymerase inhibitors. They work by blocking a protein that hepatitis C produces. Medical experts have approved the drug to treat four genotypes, 1, 2, 3 and 4. In each clinical trial, treatment regimens comprising Sofosbuvir had proper cure rates that range from 56% to more than 90%.
In the World Journal of Virology, a study published in the year 2017 in November, speaks about comparable, valid real-world rates of cure for the concerned regimens.
Depending on individual patient needs, doctors recommend Sofosbuvir in a combination with Ribavirin and pegylated interferon, Ribavirin alone, or in combination with other antiviral drugs. The last one is getting increasingly popular now.
What the lab results say
If your liver damage is severe, your only solution has to be operated. There are many renowned organizations that conduct a plethora of vitro studies and continuing research for demonstrating the fact that only the main amino acid type or S282T from the acid chain has the capacity to reduce the inhibitory properties of Sofosbuvir.
The basic properties:
It goes beyond saying that Sofosbuvir has emerged to be a prominent analogue inhibitor of nucleoside components. The drug evenly constitutes a strong and distinct resistance profile and cover. The most remarkable thing about the profile and properties of Sofosbuvir is that it doesn’t overlap or comingle with the auxiliary non-nucleoside inhibitors existing in the protease inhibitor. That’s how it can play such a long-term role. The drug is viable and potent. FDA has approved Sofosbuvir for treatment similar potential conditions.
Treatment of chronic hepatitis:
With more and more research and developments coming up in the field of medicine, and the innovations that mark them, Sofosbuvir will surely experience more studies and experiments with it. Currently, it stands a formidable therapy for HCV.
Treatment for chronic or long-term hepatitis primarily depends on the consistent deposition or accumulation of the virus in your body. In indirectly causes liver damage and problems. The main purpose of the therapy is to impede the virus from spreading to other parts of the body. The drug blocks or chokes its expansion.
On the medication:
Sofosbuvir comes in the form of pills. They are exemplary antiviral medicines to combat an active virus. The pills have proven to check and control the risk of liver damage. Its main function is to curb or lower the virus’s strength, preventing its expansion. You need to remember that doctors don’t recommend antiviral therapy for anyone living with chronic HCV. The person has to meet certain conditions and medical directives.
On the recommendations:
While dealing with a drug like Sofosbuvir, the key lies in its usage, duration, timing and recommendation from the experts. World Health Organization or WHO recommends doctors to treat HCV with this drug. It’s a mega medicine, which despite not being a permanent cure, sure has the ability to stop the virus from growing and spreading to other parts of the body.
What’s the road ahead?
The future of Sofosbuvir largely depends on the research and subsequent innovations happening with its composition and administering.
